Paul A. Offit, M.D.m Bonnie Fass-Offit, M.D. and Louis M. Bell, M.D.
See book keywords and concepts |  Children infected with rotavirus usually develop symptoms of fever and vomiting followed by diarrhea one or two days later. So, some of the children that doctors see in the winter will have only fever and vomiting. But fever and vomiting can also be the first symptoms of bacterial meningitis. The biggest difference between bacterial meningitis and early rotavirus infection is that children with bacterial meningitis will not bend their neck because of the pain. |
Gary Null, Ph.D.
See book keywords and concepts |  A significant decrease in murine rotavirus shedding was seen in litters in treated with Bifidobacterium as well.
—L.C. Duffy, et al., "Effectiveness of Bifidobacterium Bifidum in Mediating the Clinical Course of Murine rotavirus Diarrhea," Pediatric Research, 35(6), June 1994, p. 690-695.
Results of this literature review found that placebo-controlled studies have shown that biotherapeutic agents such as Lactobacillus caseiGG, Bifidobacterium longum, B longum with L acidophilus, and Saccharomyces boulardii have been effective in the prevention of antibiotic-associated diarrhea. | | Feeding of Bifidobacterium Bifidum and Streptococcus Thermophilus to Infants in Hospital for Prevention of Diarrhoea and Shedding of rotavirus," Lancet, 344(8929), October 15, 1994, p. 1046-1049.
In this study, human Bifidobacterium sp strain bifidum was given to lactating mice and their litters in order to assess strain's adherent properties and ability to inhibit murine rotavirus infection. Results found that following the administration of the high dose of virus, diarrhea developed in all pups. | | Diarrhea
Results of this double-blind, placebo-controlled study showed that infant formula supplemented with Bifidobacterium bifidum and Streptococcus thermophilus decreased the incidence of acute diarrhea and rotavirus shedding in hospitalized infants.
—J.M. Saavedra, et al.,' 'Feeding of Bifidobacterium Bifidum and Streptococcus Thermophilus to Infants in Hospital for Prevention of Diarrhoea and Shedding of rotavirus," Lancet, 344(8929), October 15, 1994, p. 1046-1049. |
Michael T. Murray, N.D., Joseph E. Pizzorno, N.D.
See book keywords and concepts |  Viruses such as rotavirus, Epstein-Barr virus, cytomegalovirus, and mycobacteria continue to be favored candidates. Other candidates include pseudomonas-like organisms, chlamydia, and Yersinia entervcolitica.
Antibiootic Exposure
Antibiotic exposure is being linked to Crohn's disease (and possibly ulcerative colitis as well1. Prior to the 1950s, Crohn's disease was found in isolated groups and had a strong genetic component. |
J. E. Williams, O.M.D.
See book keywords and concepts |  However, one Canadian team screened over one hundred plants for antiviral activity and found that lomatium completely inhibited the cytopathic effects of rotavirus (common diarrhea-causing viruses). Lomatium is used as a tincture: 1-3 ml taken three times daily. The resin fraction can cause a whole-body rash even in moderate amounts, so if you use this herb, discontinue it immediately if you feel any itching or notice a rash. |
Gary Null, Ph.D.
See book keywords and concepts | | Effectiveness of Bifidobacterium Bifidum in Mediating the Clinical Course of Murine rotavirus Diarrhea," Pediatric Research, 35(6), June 1994, p. 690-695.
Results of this literature review found that placebo-controlled studies have shown that biotherapeutic agents such as Lactobacillus caseiGG, Bifidobacterium longum, B longum with L acidophilus, and Saccharomyces boulardii have been effective in the prevention of antibiotic-associated diarrhea. Bifido-bacterum bifidum with Streptococcus thermophilus can prevent acute infantile diarrhea.
—G.W. Elmer, et al., "Biotherapeutic Agents. |
Linda B. White, M.D.
See book keywords and concepts |  Studies show that taking various strains of lactobacilli can help prevent cases of, and improve recovery from, diarrhea caused by a virus called rotavirus. They work in several ways: by out-competing undesirable bacteria and preventing "bad" bacteria from clinging to the intestinal lining, by strengthening local immune response in the gut, and by stimulating white blood cells.
You can ingest these bacteria when you eat active-culture yogurt or kefir (a yogurt drink). Just make sure the fine print on the label says the product contains live cultures. |
Schuyler W. Lininger, Jr. DC
See book keywords and concepts |  Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus. Lancet 1994; 344: 1046-49.
98. Kudsk KA, Minard G, Croce MA, et al. A randomized trial of isoni-trogenous enteral diets after severe trauma. An immune-enhancing diet reduces septic complications. Ann Surg 1996; 224: 531-40.
99. Braga M, Gianotti L, Cestari A, et al. Gut function and immune and inflammatory responses in patients perioperatively fed with supplemented enteral formulas. Arch Surg 1996; 131: 1257-64.
100. |
Textbook of Natural Medicine 2nd Edition Volume 2Michael T. Murray, ND
See book keywords and concepts | | Viruses, such as rotavirus, Epstein-Barr virus, cytomegalovirus, and an uncharacterized RNA intestinal cytopathic virus, and mycobacteria continue to be favored candidates. Other candidates include:1,2,5"7
• Pseudomonas-like organisms
• enteric anaerobes
• Chlamydia
• Yersinia enterocolitica.
Antibiotic exposure
Antibiotic exposure is being linked to Crohn's disease.1 Prior to the 1950s, Crohn's disease was found in selected groups with a strong genetic component. |
Sheldon Saul Hendler and David Rorvik
See book keywords and concepts |  Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum. Pediatr Infect Dis J. 1998; 17:1149-1154.
Tacket CO, Binion SB, Bostwick E, et al. Efficacy of bovine milk immunoglobulin concentrate in preventing illness after Shigellla flexneri challenge. Am J Trop Med Hyg. 1992; 47:276-283.
Tacket CO, Losonsky G, Livio S, et al. Lack of prophylactic efficacy of an enteric-coated bovine hyperimmuune milk product against enterotoxigenic Escherichia coli challenge administered during a standard meal. J Infect Dis. 1999; 180:2056-2059. | | Other researchers have demonstrated that the incidence of acute diarrhea and rotavirus shedding can be significantly reduced among infants admitted to the hospital by adding Bifidobacterium bifidum and Streptococcus thermophilus to infant formula. Lactobacillus GG has been shown helpful in the treatment of diarrhea associated with relapsing colitis due to Clostridium difficile. These studies, however, were small and uncontrolled. | | This effect may account, in part, for the stimulation of IgA responses in infants infected with rotavirus. In healthy individuals, Lactobacillus salivarius UCC118 and Lactobacillus johnsonii LAI were demonstrated to produce an increase in the phagocytic activity of peripheral blood monocytes and granulocytes. Also, Lactobacillus johnsonii LAI, but not Lactobacillus salivarius UCC118, was found to increase the frequency of interferon-gamma-producing peripheral blood monocytes.
Lactobacillus GG has been shown to inhibit chemically induced intestinal tumors in rats. | | Hyperimmune bovine colostrum is rich in immunoglobulins of the IgG type, which are protective against such infectious microorganisms as Cryptosporidium parvum (a major cause of AIDS-associated diarrhea), diarrheogenic Escherichia coli strains, Shigella flexneri, Clostridium difficile, and rotavirus, the most common cause of severe diarrhea in young children.
Hyperimmune bovine colostmm is prepared from cows previously immunized with specific antigens. | | Lactobacillus GG was found to eradicate Clostridium difficile in patients with relapsing colitis, and supplementation of infant formula milk with Bifidobacterium bifidum and Streptococcus thermophilus reduced rotavirus shedding and episodes of diarrhea in hospitalized children.
The antimicrobial activity of probiotics is thought to be accounted for, in large part, by their ability to colonize the colon and reinforce the barrier function of the intestinal mucosa. |
Paul A. Offit, M.D.m Bonnie Fass-Offit, M.D. and Louis M. Bell, M.D.
See book keywords and concepts | | The biggest difference between bacterial meningitis and early rotavirus infection is that children with bacterial meningitis will not bend their neck because of the pain. But, some children with bacterial meningitis will not develop neck pain at the beginning of their illness and in younger children discerning neck pain can be very difficult. If a doctor sees a patient with fever and vomiting, and the patient moves her neck without difficulty, the doctor will be reassured that this is probably a viral infection. |
James A. Howenstine, MD
See book keywords and concepts |  In 1999, rotavirus vaccine was recommended by the Centers for Disease Control for all infants. When this vaccine program was instituted several infants died and many had life endangering bowel obstructions. Obviously, there was no evidence that this vaccine would cause such serious problems before the vaccine was released for usage.
The pertussis (whooping cough) vaccine has been responsible for 70% of the claims in the Vaccine Injury Program and Compensation program. |
Jean Carper
See book keywords and concepts |  This milk contains antibodies to the rotavirus or the bacteria E. coli, and can help prevent certain intestinal infections, especially among children."
Forced to choose, Dr. Yolken would settle on eggs as the favored vehicle for antibody distribution because they are cheaper, more commonly eaten in the world, and are less apt to cause allergic reactions. Many people in third world countries cannot tolerate milk proteins. For an extra-potent antiinfective drink, of course, you could mix milk and eggs. "The antibody effects would be at least additive," says Dr. Yolken. |
Schuyler W. Lininger, Jr. DC
See book keywords and concepts | | Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus. Lancet 1994; 344: 1046-49.
19. Colombel JF, Cortot A, Neut C, Romond C. Yogurt with Bifidobacterium longum reduces erythromycin-induced gastrointestinal effects. Lancet 1987; ii: 43 [letter].
20. Montes RG, Perman JA. Lactose intolerance. Postgrad Med 1991; 89: 175-84 [review].
21. Werbach MR. Nutritional influences on Illness, 2d ed. Tarzana, CA: Third Line Press, 1993, 256-61 [review].
22. Bhan J, Bhandari N. |
Jean Carper
See book keywords and concepts | | Yolken and his colleagues are searching for cheap, safe agents to combat a particular type of virus called a rotavirus, primarily responsible for the infection.
That led him to flirtations with some novel ideas and to a surprising discovery among the milk herds of Maryland.
Perhaps only a professor keeps forward in his mind the fact that antibodies can enter a body two ways. Your immune system makes its own. These are "active antibodies"; they remember the foreign invader forever. Vaccines—which are low doses of antigens—force your body to create active antibodies. | | They then put dabs of the diluted milk samples in test tubes lined with rotavirus antigen; any antibodies present in the milk would latch on to the viral attractions, and sophisticated detection equipment could measure how many were there. As Dr. Yolken perused the printouts of the lab tests, he noticed that raw milk was full of antibodies. No surprises there. But he was startled by the numbers from the pasteurized samples. He thought it must be a mistake. The pasteurized milk showed extensive antibody activity too. Fully seventy-seven percent of the antibodies had escaped destruction. | | So the stuff everybody drinks was infused with rotavirus antibodies. "It's clear antibody molecules are fairly hardy and can survive processing that renders milk suitable for consumption," he reported. Furthermore, a couple of weeks in a refrigerator had slight effect on pasteurized milk's antibodies. But alas, the processing temperatures had totally annihilated antibodies in all twenty-one commercial infant formulas. Very few antibodies also survived in sterilized nonrefrigerated "shelf' milk, common in European countries. | | All sixteen mice exposed only to the rotavirus developed infections. None of the eight that got the virus-raw milk concoction, with the most antibodies, showed signs of infection. And only one of eight drinking the pasteurized milk plus virus got the expected diarrhea. Clearly the milk with antibodies successfully bestowed a high degree of passive immunity. The luckless mice given the infant formula, devoid of antibodies, all got sick.
Moreover, there was a critical dose response. The milk with the most antibody activity was the most protective against infection. | | They inoculated chickens with a low dose of rotavirus. Then for the next two or three weeks they gathered eggs laid in the Johns Hopkins laboratories by the chickens, whipped up the yolks, extracted their immunoglobulin, and gave it along with viruses to the mice. The eggs had twenty times the antibodies that nature had provided. Not a single mouse came down with infection.
Dr. Yolken sees chickens as a virtual antibody factory. He notes that a single chicken could provide up to thirty kilograms of immunoglobulin a year. |
Phyllis A. Balch, CNC
See book keywords and concepts |  Laboratory tests in Korea have found that bitter orange extracts are especially effective in killing rotavirus, the organism that causes viral diarrhea in children.
Benefits of bitter orange for specific health conditions include the following:
• Anemia. Bitter orange contains generous amounts of vitamin C and can be beneficial for anemia if vitamin C is needed to provide the acidic environment necessary for iron absorption.
• Heart attack, heat stress, and high blood pressure. |
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